442 FEMALE RATS SHOW A GREATER BEHAVIORAL RESPONSE TO HEROIN ACROSS SELF-ADMINISTRATION AND LOCOMOTOR SENSITIZATION COMPARED TO MALES

442 Female rats show a greater behavioral response to heroin across self-administration and locomotor sensitization compared to males

Objectives/Goals: Men and women with opioid use disorder (OUD) show differences in their initiation, use patterns, and outcomes that may have biological underpinnings.Here we present data directly comparing adult male and female rats across heroin-induced behaviors in order to provide insight into the nuances of sex differences in OUD.Methods/Study

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Common Risk Factors for Urinary House Soiling (Periuria) in Cats and Its Differentiation: The Sensitivity and Specificity of Common Diagnostic Signs

Urinary house soiling (periuria) in the home is a common but serious behaviour problem in cats.Although many specific risk factors and triggers have been postulated, their importance is largely unknown.This study assessed: (1) the significance of purported risk factors for periuria as well as specifically marking and latrine behaviour in the home;

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Pathways to a cancer-free future: a protocol for modelled evaluations to minimise the future burden of colorectal cancer in Australia

Introduction With almost 50% of cases preventable and the Australian National Bowel Cancer Screening Program in place, colorectal cancer (CRC) is a prime candidate for investment to reduce the cancer burden.The challenge is determining effective ways to reduce morbidity and mortality and their implementation through policy and practice.Pathways-Bow

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