442 Female rats show a greater behavioral response to heroin across self-administration and locomotor sensitization compared to males
Objectives/Goals: Men and women with opioid use disorder (OUD) show differences in their initiation, use patterns, and outcomes that may have biological underpinnings.Here we present data directly comparing adult male and female rats across heroin-induced behaviors in order to provide insight into the nuances of sex differences in OUD.Methods/Study